Agenda – Canadian CLL

(Open In-Person to Patients & Patient Advisory Board Members Only)

9:15 – 10:00	Registration
10:00 – 10:05	Opening Remarks – Dr. Versha Banerji, Manitoba CLL Chair
10:05 – 10:20	Welcome from CancerCare Manitoba – Dr. Donna Turner, Interim President and CEO CancerCare Manitoba
10:20 – 10:30	From the Patient Perspective – Three Words Nobody Wants to Hear – Philipa Caplan, CLL Canada

10:30 – 11:00	Keynote – CLL 101 for Patients – Dr. Chris Hillis, Vice President Oncology and Site Executive, Hamilton Health Sciences
11:00 – 11:15	Coffee Break
11:15 – 11:25	CLL and the Immune System (Nuts & Bolts) – Dr. Lin Yang, Hematologist, CancerCare Manitoba
11:25 – 11:35	Leveraging the Immune System for CLL Directed Treatment: Chimeric Antigen Receptor (CAR) T-cell Therapy and Bispecific Antibodies – Dr. Ivan Landego, Hematologist, CancerCare Manitoba
11:35 – 11:45	Richter’s Transformation – Dr. Lin Yang, Hematologist, CancerCare Manitoba
11:45 – 12:05	Ask the Experts – Dr. Lin Yang & Dr. Ivan Landego & Dr. Chris Hillis
12:05 – 12:15	Manitoba Tumour Bank – Nicole Wozny, CancerCare Manitoba
12:15 – 13:10	Lunch

13:10 – 13:20	Geroscience – Investigating the Mechanisms of Aging and Frailty -Dr. David Dawe, Medical Oncologist, CancerCare Manitoba
13:20 – 13:30	The Clinical Trials Unit – Dr. Pamela Skrabek, Chair, Lymphoproliferative Disease Site Group, CancerCare Manitoba
13:30 13:40	Patient Talk Presentation: Clinical Trials Update in Manitoba/International Collaboration; The Ignite Project – Dr Versha Banerji, Manitoba CLL Chair
13:40 -13:50	Introduction to the Microbiome – Dr. Alicia Berard, University of Manitoba
13:50 – 14:00	Chronic Lymphocytic Leukemia: Nurse Led Clinic – Brittany Kasloff, RN, CancerCare Manitoba
14:00 – 14:20	Coffee Break
14:20 – 14:30	Real World Evidence with Venetoclax-Obinutuzumab for Front Line Therapy in CLL: A Canadian Centralized CLL Clinic Experience – Dr. Lin Yang, Hematologist, CancerCare Manitoba & Dr. Ortenc Hoxha, PGY5 Hematology Fellow, Western University
14:30 – 14:40	Website Launch – Jennifer Jochem, University of Manitoba
14:40 – 14:50	Patient Engagement & Info Session Closing Remarks – Dr. Versha Banerji, Manitoba CLL Chair

End of Patient Participation

(Open to CLL Researchers, Clinicians, Trainees & Sponsors Only)

17:00 – 18:30	Manitoba CLL Poster Presentation Reception Judges: Dr. Lin Yang, Dr. Chris Hillis
18:30 – 21:30	Manitoba CLL Dinner – Chair: Dr. Versha Banerji
18:30 – 18:35	Welcome – Dr. Versha Banerji, Manitoba CLL Chair
18:35 – 18:45	Empowering Patients from a Patient Perspective – Philipa Caplan, CLL Canada
18:45 – 18:55	Award Poster Prizes – Ms. Donna Simister
18:55 – 19:15	Not in my Differential: Career Surprises I Didn’t See Coming – Dr. Chris Hillis, Vice President Oncology and Site Executive, Hamilton Health Sciences

(Open to CLL Researchers, Clinicians, Trainees & Sponsors Only)

8:00 – 9:00	Breakfast & Registration
9:00– 9:05	Opening Remarks

9:05 – 9:40	Mapping CLL at Scale: Profiling Hundreds of CLL Patient Samples Using Integrated MS-Based Proteomics, Phosphoproteomics, and Machine Learning – Dr. Rene Zahedi, Director, Manitoba Centre for Proteomics
9:40 – 9:50	DNA-PK Inhibition: An Unexpected but Effective Target to Fight Venetoclax-Resistant CLL– Clare Hibbert, University of Manitoba
9:50 – 10:00	Update: Investigating Blood-Based Biomarkers of Frailty in Patients with Chronic Cancer – Dr. Versha Banerji, Manitoba CLL Chair
10:00 – 10:10	Update: Sex Dimorphism in Chronic Lymphocytic Leukemia – Correlating with Biomarkers of Frailty and CIRS Score – Dr. Julie Hong, PGY-4, University of Manitoba
10:10 – 10:25	Impact of Systemic Metabolic Dysfunction on Cellular Metabolism in Chronic Lymphocytic Leukemia – Asim Ibrahim, MS2, University of Manitoba
10:25 – 10:40	An Update on the CLIME Study; Examining the Association Between Infection and CLL – Dr. Kathleen Decker, Senior Scientist and Director, Health Services Research Lab, Paul Albrechtsen Research Institute CancerCare Manitoba
10:40 – 11:00	Coffee Break

11:00 – 11:15	Update on TFRI Project/Ignite, Answering Clinical Questions Using Big Data- Positioning Ourselves to Be Leaders – Dr. Versha Banerji, Manitoba CLL Chair
11:15 – 11:30	Exploring Type III Interferon Biology in Human B Cells and the Implications in CLL – Dr. Deanna Santer, University of Manitoba
11:30 – 11:45	From Real Time to Virtual Worlds: Leveraging Technology to Understand and Support Mental Health in Cancer Care – Dr. Renee El-Gabalawy, University of Manitoba
11:45 – 12:00	Understand the Metabolic Health of Your Blood Vessels – Dr. Carla Taylor, Principal Investigator, Metabolic Nutrition Laboratory, CCARM
12:00 – 12:15	Integrating AI into Health Algorithms – Dr. Lei Ding, , Assistant Professor, University of Manitoba
12:15 – 12:30	Understanding the Microbiome – Dr. Alicia Berard, University of Manitoba
12:30 – 13:30	Lunch

13:30 – 13:45	Flow Cytometry: Exploring T Cell Phenotypes in CLL – Dr. Rebecca Dielschneider, Associate Professor, Providence University College & Dr. Aaron Marshall, Professor and Head, Department of Immunology, University of Manitoba
13:45 – 14:00	Manitoba Genomics Platform: Illumina Sequencing Services for Mouse Models of Lymphocytic Leukemias – Dr. Jay Kormish, CancerCare Manitoba
14:00 – 14:15	CAR T Production – Dr. David Szwajcer, Assistant professor, Max Rady College of Medicine
14:15 – 14:30	Advancing Bioinformatics Approaches for Multi-Omics Analysis – Dr. Athanasios Zovoilis, University of Manitoba
14:30 – 14:45	Beyond Service: A Translational Proteomics Engine – Dr. Rene Zahedi, Director, Manitoba Centre for Proteomics
14:45 – 14:50	Closing Remarks – Dr. Lin Yang
14:50 – 15:35	Break

(Open to CLL Researchers, Clinicians & Presenting Industry Sponsors Only)

Pipeline MTS – Allocated Time Slots w/ Sponsor Companies – Chair: Dr. Versha Banerji